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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Feature-based classification of human transcription factors into hypothetical sub-classes related to regulatory function

Fig. 2

- Important properties for classification. The plot shows RF feature importance and AUC score for each property for the classification of each functional class (Pioneers (P), Settlers (S), positive Migrants (M+) and negative Migrants (M-)) versus Rest. This highlights the importance of structural TF classification (TFClass) and Pfam domains (PD) for correct classification of regulatory function. The other properties are DNA binding domain (DBD), number of DBDs (N_DBD), protein-protein interaction (PPI), number of PPIs (N_PPI), post-translational modifications, both in general (PTM) and as individual modifications (Ind_PTM), number of frequent zinc finger domains (N_ZFD) and number of positions for phosphorylation (N_PhS)

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BMC Bioinformatics

ISSN: 1471-2105

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