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Table 3 Experimental data and classification results according to TFClass

From: Feature-based classification of human transcription factors into hypothetical sub-classes related to regulatory function

   Total Experimental Classified Average p-value
TFClass Code #TFs #TFs P S M+ M- #TFs P S M+ M- All Margin
Uncharacterized 0.0 6 0 0 0 0 0 6 0 5 1 0 0.682 0.027
NonO domain factors 0.2 2 0 0 0 0 0 2 0 2 0 0 0.679 0.022
Leucine-rich repeat proteins 0.3 1 0 0 0 0 0 1 0 1 0 0 0.679 0.022
NFX1-type putative zf factors 0.4 3 0 0 0 0 0 3 1 2 0 0 0.673 0.016
bZIP 1.1 54 25 2 9 3 11 29 10 9 0 10 0.720 0.150
bHLH 1.2 84 29 1 23 3 2 55 0 55 0 0 0.943 0.539
bHSH 1.3 4 1 1 0 0 0 3 3 0 0 0 0.759 0.128
Nuclear receptors with C4 zfs 2.1 47 47 1 1 45 0 0 0 0 0 0 - -
Other C4 zfs 2.2 17 4 0 0 1 3 13 0 0 0 13 0.738 0.056
Three-zf Kruppel-related factors 2.3.1 26 5 4 1 0 0 21 21 0 0 0 0.958 0.273
Other factors with 3 adjacent zf 2.3.2 15 0 0 0 0 0 15 12 0 3 0 0.773 0.203
More than 3 adjacent zf 2.3.3 327 12 6 1 4 1 315 201 0 114 0 0.862 0.213
Factors multiple dispersed zf 2.3.4 103 5 1 2 1 1 98 35 58 5 0 0.765 0.086
DM-type intertwined zf factors 2.5 6 0 0 0 0 0 6 0 0 6 0 0.704 0.166
CXXC zf factors 2.6 7 0 0 0 0 0 7 0 0 7 0 0.704 0.112
C2HC zf factors 2.7 8 0 0 0 0 0 8 0 0 8 0 0.704 0.116
C3H zf factors 2.8 2 0 0 0 0 0 2 0 0 2 0 0.704 0.116
C2CH THAP-type zf factors 2.9 1 0 0 0 0 0 1 0 0 1 0 0.704 0.084
Homeo domain factors 3.1 198 198 0 0 3 195 0 0 0 0 0 - -
Paired box factors 3.2 9 5 0 1 1 3 4 0 1 2 1 0.735 0.181
Fork head 3.3 56 56 2 3 1 50 0 0 0 0 0 - -
Heat shock factors 3.4 5 0 0 0 0 0 5 0 5 0 0 0.683 0.120
Tryptophan cluster factors 3.5 50 34 23 3 7 1 16 0 0 16 0 0.937 0.264
TEA domain factors 3.6 4 1 0 0 1 0 3 0 0 3 0 0.808 0.152
ARID domain factors 3.7 12 1 0 0 0 1 11 1 10 0 0 0.631 0.012
HMG domain factors 4.1 41 19 0 0 2 17 22 0 0 0 22 0.741 0.338
Het. CCAAT-binding factors 4.2 4 2 2 0 0 0 2 2 0 0 0 0.817 0.357
MADS box factors 5.1 5 2 0 0 0 2 3 0 0 0 3 0.650 0.014
SAND domain factors 5.3 7 3 1 0 2 0 4 0 0 4 0 0.906 0.304
RHR factors 6.1 21 3 0 1 2 0 18 0 0 18 0 0.907 0.125
STAT domain factors 6.2 7 0 0 0 0 0 7 0 0 7 0 0.777 0.076
p53 domain factors 6.3 3 0 0 0 0 0 3 0 0 3 0 0.777 0.062
Runt domain factors 6.4 3 0 0 0 0 0 3 0 0 3 0 0.777 0.062
T-Box factors 6.5 16 1 0 1 0 0 15 0 12 3 0 0.814 0.071
Grainyhead domain factors 6.7 4 0 0 0 0 0 4 0 0 4 0 0.777 0.122
SMAD/NF-1 DBD factors 7.1 8 1 1 0 0 0 7 3 4 0 0 0.761 0.211
GCM domain factors 7.2 2 1 0 1 0 0 1 0 1 0 0 0.844 0.268
TATA-binding proteins 8.1 2 1 0 0 1 0 1 0 0 1 0 0.805 0.171
AT hook factors 8.2 2 1 0 0 0 1 1 0 1 0 0 0.634 0.001
Cold-shock domain factors 9.1 3 0 0 0 0 0 3 0 3 0 0 0.679 0.022
Sum - 1175 457 45 47 77 288 718 289 169 211 49   
  1. The results are shown for Pioneers (P), Settlers (S), positive Migrants (M+) and negative Migrants (M-)