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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23

Fig. 5

Phage display experiment. a Structure of the peptide scaffold for phage library 1KATr1. Variable residue positions are colored red, and disulfide bonds in yellow. The same representation is used for the 1KVFr1 (b) and 1ZDCr1 (c) library scaffolds. d Enrichment ratios across successive rounds of phage panning for the three libraries. Panning was discontinued after the fourth round for 1KATr1 and 1KVFr1 due to a lack of enrichment. e Standard curve resulting from competition ELISA experiment to assess inhibition of IL-23/IL-23R complex formation by the PN-05-84 clone

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BMC Bioinformatics

ISSN: 1471-2105

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