Table 4 Variances of specificity, sensitivity, accuracy, and MCC for both 5p and 3p arms by five-fold cross-validation using PHDCleav and LBSizeCleav (k=1,⋯,5) with window sizes 8,10,12,14 based on sequences and secondary structures predicted by quikfold server

PHDCleav (sequence)

8

0.0137

0.0008

0.0074

0.0036

0.0072

0.0015

0.0094

0.0066

10

0.0184

0.0004

0.0111

0.0018

0.0044

0.0005

0.0072

0.0024

12

0.0208

0.0001

0.0223

0.0003

0.0078

0.0011

0.0031

0.0046

14

0.0293

0.0009

0.0174

0.0037

0.0065

0.0007

0.0048

0.0029

PHDCleav (structure)

8

0.0042

0.0039

0.0067

0.0155

0.0187

0.0013

0.0091

0.0062

10

0.0026

0.0043

0.0088

0.0177

0.0100

0.0014

0.0050

0.0059

12

0.0042

0.0027

0.0034

0.0109

0.0051

0.0011

0.0024

0.0045

14

0.0047

0.0031

0.0034

0.0125

0.0039

0.0012

0.0014

0.0047

Extended PHDCleav

8

0.0029

0.0032

0.0063

0.0128

0.0123

0.0025

0.0043

0.0103

10

0.0030

0.0038

0.0061

0.0154

0.0064

0.0019

0.0016

0.0075

12

0.0040

0.0033

0.0050

0.0136

0.0054

0.0015

0.0011

0.0059

14

0.0059

0.0027

0.0016

0.0108

0.0032

0.0013

0.0010

0.0052

LBSizeCleav (k=1)

8

0.0030

0.0025

0.0044

0.0115

0.0100

0.0004

0.0074

0.0019

10

0.0022

0.0015

0.0013

0.0064

0.0078

0.0011

0.0015

0.0042

12

0.0050

0.0024

0.0010

0.0090

0.0077

0.0015

0.0002

0.0051

14

0.0075

0.0035

0.0010

0.0132

0.0036

0.0007

0.0002

0.0026

LBSizeCleav (k=2)

8

0.0042

0.0018

0.0008

0.0066

0.0053

0.0010

0.0036

0.0041

10

0.0038

0.0020

0.0009

0.0076

0.0034

0.0010

0.0010

0.0039

12

0.0051

0.0029

0.0016

0.0115

0.0042

0.0017

0.0008

0.0063

14

0.0051

0.0028

0.0012

0.0107

0.0043

0.0008

0.0002

0.0024

LBSizeCleav (k=3)

8

0.0025

0.0013

0.0008

0.0050

0.0070

0.0010

0.0021

0.0042

10

0.0039

0.0022

0.0012

0.0086

0.0064

0.0013

0.0006

0.0048

12

0.0063

0.0031

0.0012

0.0119

0.0039

0.0015

0.0005

0.0055

14

0.0060

0.0033

0.0015

0.0130

0.0073

0.0016

0.0003

0.0046

LBSizeCleav (k=4)

8

0.0029

0.0016

0.0009

0.0064

0.0066

0.0020

0.0030

0.0078

10

0.0046

0.0025

0.0011

0.0095

0.0071

0.0014

0.0006

0.0049

12

0.0061

0.0032

0.0014

0.0124

0.0033

0.0011

0.0007

0.0041

14

0.0051

0.0030

0.0015

0.0120

0.0088

0.0025

0.0002

0.0082

LBSizeCleav (k=5)

8

0.0029

0.0017

0.0009

0.0066

0.0062

0.0021

0.0031

0.0082

10

0.0055

0.0029

0.0013

0.0113

0.0032

0.0011

0.0005

0.0042

12

0.0051

0.0029

0.0015

0.0114

0.0029

0.0011

0.0009

0.0044

14

0.0047

0.0029

0.0016

0.0116

0.0076

0.0023

0.0002

0.0076