Fig. 8
From: A methodological approach for using high-level Petri Nets to model the immune system response
Detailed dynamics of specific immune system entities in the PN model (a) and the UISS framework (b). At the time of the second bacteria injection (timestep 400), the total level of IgG (dashed red line) is much higher in respect to the level measured at the time of the first injection. As a result of this, bacteria (dotted green line) are cleared more rapidly at the time of the second injection. Both IgM (solid cyan line) and IgG (dashed red line) levels obtained with the PN model (a) are in good agreement (from a qualitative point of view) with the results obtained by using the UISS framework (b)