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Table 1 Nodes of the network

From: Statistical ensemble of gene regulatory networks of macrophage differentiation

Input

Receptor

Internal nodes

Phenotype

References

LPS

TLR4

NF-kB, NOS2

M1

[2023, 2530, 38]

IFNg

IFNgR

STAT1, SOCS3, NOS2

M1

[2023, 2530, 38]

IL-4

IL-4Ra

STAT6, PPARg,

M2

[23, 24, 3138]

  

SOCS1, KLF4, Arg1

  

IL-10

IL-10R

STAT3

M2

[23, 24, 3138]

  1. Internal nodes means transducers/transcription factors/target genes