BMC Bioinformatics

Table 1 Nodes of the network

From: Statistical ensemble of gene regulatory networks of macrophage differentiation

Input	Receptor	Internal nodes	Phenotype	References
LPS	TLR4	NF-kB, NOS2	M1	[20–23, 25–30, 38]
IFNg	IFNgR	STAT1, SOCS3, NOS2	M1	[20–23, 25–30, 38]
IL-4	IL-4Ra	STAT6, PPARg,	M2	[23, 24, 31–38]
		SOCS1, KLF4, Arg1
IL-10	IL-10R	STAT3	M2	[23, 24, 31–38]

Internal nodes means transducers/transcription factors/target genes

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ISSN: 1471-2105

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