A hydrophobic spine stabilizes a surface-exposed α-helix according to analysis of the solvent-accessible surface area

Table 3 The feature usage and a performance summary from other studies that used Barton502 as a dataset

features	Ours	Chang, et al. (2008)^a	Nguyen, et al. (2006)^a	Garg, et al. (2005)^a	Wang, et al. (2005)^a	Yuan, et al. (2004)^a	Ahmad, et al. (2003)^a
PSSM	Yes	Yes	Yes	Yes	Yes	No	No
AAindex (PCPs)	Yes	No	No	No	No	No	No
sequence length	Yes	Yes	No	No	Yes	No	No
amino acid composition	No	No	No	No	No	Yes	Yes
secondary structure	No	No	No	Yes	No	No	No
regression tool	one-stage SVR	two-stage SVR	two-stage SVR	NN	MLR	one-stage SVR	NN
MAE (%)	14.11	14.80	15.70	15.90	16.20	18.50	18.80
CC	0.69	0.68	0.66	0.65	0.64	0.52	0.48

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