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Table 5 Various CK-1δ residues involved in different kinds of interactions with CHC and DHC

From: Novel group-based QSAR and combinatorial design of CK-1δ inhibitors as neuroprotective agents

Complex

Residues involved in hydrophobic interactions

Residues involved in hydrogen bonding

CK-1δ-CHC

Ile23, Met82, Leu84, Leu85, Gly86, Pro87, Asp91, Leu135, Ile148, Asp149

Lys38, Glu52, Tyr56

CK-1δ-DHC

Gly21, Ile23, Ala36, Met82, Leu85, Gly86, Pro87, Phe95, Lys130, Asn133, Leu135, Ile148, Asp149

Lys38, Asp91