Skip to main content
Fig. 11 | BMC Bioinformatics

Fig. 11

From: Robust differential expression analysis by learning discriminant boundary in multi-dimensional space of statistical attributes

Fig. 11

Some positive TaqMan genes have complex distributions in technical replicates (the 1st library of sample B). Y-axis: the correlation coefficients between the normalized-count distributions and the corresponding fitted GMM distribution. X-axis: the correlation coefficients between the normalized-count distributions and the corresponding fitted NB distribution. Each dot represents a gene. The distribution of a gene’s normalized counts is approximated by a histogram of 20 equal-size bins spanning its read-count value range. The colors of dots indicate the most proper numbers of components in a fitted GMM according to the Bayesian Information Criterion: green (~67.5%), blue (~21.8%), and red (~10.7%) correspond to 1, 2 and 3 components, respectively

Back to article page