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Fig. 9 | BMC Bioinformatics

Fig. 9

From: Integrating mean and variance heterogeneities to identify differentially expressed genes

Fig. 9

Background data structure of the expression levels of robust gene probes. From the MAS5 normalized data, we selected 13,415 robust gene probes and conducted background PCA. PC1 alone accounted for 98.35% of the total variation and was the unique major PC. PC2 merely accounted for 0.37% of total variation. Neither PC1 nor PC2 displayed mean heterogeneity or variance heterogeneity. PC14 displayed significant mean heterogeneity (p WT  = 0.0036), even if it only accounted for 0.03% of the total variation. PC28 displayed significant variance heterogeneity (p LF  = 0.0069) even if it accounted for 0.01% of the total variation only. PC14 and PC28 displayed clear stratification of the smokers and the nonsmokers. a Variation proportions, b PC1 and PC2, c PC14 and PC28

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