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Fig. 3 | BMC Bioinformatics

Fig. 3

From: STON: exploring biological pathways using the SBGN standard and graph databases

Fig. 3

Linking networks in PD and AF representations. The figure shows different levels of granularity of the iNOS pathway in PD (green background) and AF (blue background). The yellow relationships represent the linking between equivalent nodes. In the PD network, IFNG binds to the IFNG receptor complex. This complex will then activate the dimerisation of STAT1alpha. In the AF network, IFNG and elements of the receptor complex (seen in the PD level) are necessary to activate STAT1alpha. In order to create a link, the compared nodes should have different file names, but same name, nodetype, compartment and unit of information. In addition, one node should be represented in the SBGN PD language and another on SBGN AF

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