Gene regulatory network inference using PLS-based methods

BMC Bioinformatics

Table 4 Performance comparisons of different GRN inference methods on the DREAM5 networks

Method	Network 1		Network 3		Network 4		Overall Score
Method	AUPR	AUROC	AUPR	AUROC	AUPR	AUROC	Overall Score
GENIE3	0.291	0.814	0.094	0.618	0.021	0.517	40.313
TIGRESS	0.302	0.783	0.070	0.596	0.020	0.517	31.112
CLR	0.254	0.771	0.075	0.591	0.020	0.516	19.387
ARACNE	0.187	0.763	0.069	0.572	0.018	0.504	9.24
NIMEFI	0.298	0.817	0.101	0.625	0.022	0.518	46.015
PLSNET	0.270	0.862	0.065	0.577	0.023	0.519	48.269
Winner of the Challenge
GENIE3	0.291	0.815	0.093	0.617	0.021	0.518	40.279
ANOVerence	0.245	0.780	0.119	0.671	0.022	0.519	34.023
TIGRESS	0.301	0.782	0.069	0.595	0.020	0.517	31.099

The best results for each column are in bold. Numbers in the “Winner of competition” part of the table correspond to the best methods participating in the challenge as listed on the DREAM web site

ISSN: 1471-2105