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Table 2 Kinetic constants for phosphorylation of p27KIP1 peptides

From: Structural prediction of the interaction of the tumor suppressor p27KIP1 with cyclin A/CDK2 identifies a novel catalytically relevant determinant

Peptide

Sequence

Km [μM]

Relative rate

[pmol/min]

Relative rate/Km

wt

N180AGSVEQTPKKPGLR

93.6

2.21

0.0195

R194A

N180AGSVEQTPKKPGLA

81.4

1.11

0.0135

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BMC Bioinformatics

ISSN: 1471-2105

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