Fig. 3

Gene activity predictions based on histone modification patterns at single gene regions for all 24 gene regions. a Histone modification patterns in CART trees generated using single gene region data were used to ascribe index values of +1 and -1 to each of the 18,729 genes, and the percent of genes with index values of +1 and -1 that were, respectively, among genes designated active and inactive based on Ymax threshold was calculated. The percent was considered the prediction accuracy frequency of the tree. The histone modifications at nodes of each gene region are shown with two (for acetylations) or three (for methylations) digits separated by dots. The first and second digits indicate histone number and the amino acid number. The third digit when present represents the number of methyl groups present. b and c Respectively, three node CART trees generated on basis of histone modification patterns of TSS and TSS-1 of 18,729 genes. + and -, respectively, signify presence or absence of modification in preceding node. See Additional file 1: Figure S4. Prediction accuracy frequency of modification patterns at TSS+2 (not shown) were much lower than those at TSS+1