Fig. 4
From: Confident gene activity prediction based on single histone modification H2BK5ac in human cell lines
Gene activity predictions on test genes based on CART trees generated with train gene data. a Histone modification patterns in CART trees with various numbers of nodes were generated using data on all 24 gene regions of approximately 10,000 training genes, and the trees were used to ascribe index values of +1 and -1 to each of the same (left columns; training) or different (right columns; test) set of genes. The percent of genes with index values of +1 and -1 that were, respectively, among genes designated active and inactive based on Ymax threshold was calculated. The percent was considered the prediction accuracy frequency of the tree. b and c Respectively, seven and five node CART trees generated by using data on all 24 gene regions of approximately 10,000 training genes. + and -, respectively, signify presence or absence of modification in preceding node. See Additional file 1: Figure S4