Table 5 Gene activity prediction capacity in IMR90, hESC-h1, and MSC cells
From: Confident gene activity prediction based on single histone modification H2BK5ac in human cell lines
Cell type | Two node CART tree based | Five node CART tree based | Five node CART tree based on | |||
|---|---|---|---|---|---|---|
Gene regions at nodes | Prediction capacity | Gene regions at nodes | Prediction capacity | Modifications & gene regions at nodes | Prediction capacity | |
IMR-90 cells | TSS+1, TSS-2 | 78.10% | TSS+1, TSS-2, TTS+4, TTS, TSS-10 | 78.10% | H3K27ac/TSS, H2BK5ac/TSS-2 H3K36me3/TTS, H3K36me3/TTS+1, H3K4me3/TSS+1 | 78.69% |
hESC-h1 cells | TSS, TSS-2 | 69.70% | TSS, TSS-2, TSS-1, TTS+1, TSS-3 | 70.00% | H3K27ac/TSS-1, H3K4me3/TSS, H2BK5ac/TSS+1, H3K27/TSS+1, H4K20me1/TSS | 74.42% |
MSC cells | TSS, TSS+1 | 63.83% | TSS, TSS+1, TSS-1 | 63.85% | H3K27me3/TSS+1, H3K36me3/TTS+1, H2BK5ac/TSS, H3K36me3/TTS, H2BK5ac/TSS | 68.38% |