Skip to main content
Fig. 2 | BMC Bioinformatics

Fig. 2

From: GTB – an online genome tolerance browser

Fig. 2

A similar trend in intolerance can be observed across LDLR using sequence- and structure-based prediction algorithms, i.e. sequence-based methods tend to agree on intolerance given that they both rely on sequence conservation whereas structure-based algorithms utilize the additional structure-based properties made available to them to show a different tolerance profile. Unlike HOXA5, genome-wide prediction algorithms appear to agree on potential peaks of intolerance across the non-coding region of LDLR

Back to article page