iGC—an integrated analysis package of gene expression and copy number alteration

BMC Bioinformatics

Table 1 The performance of the iGC and SIM packages in different scenarios

Scenario	Gene number	Sample size	iGC sensitivity (mean ± sd)	iGC specificity (mean ± sd)	SIM sensitivity (mean ± sd)	SIM specificity (mean ± sd)
1	100	50	0.6293 ± 0.075	0.8764 ± 0.025	0.2582 ± 0.1118	0.7527 ± 0.0373
2	100	100	0.7283 ± 0.0651	0.9094 ± 0.0217	0.3503 ± 0.0817	0.7834 ± 0.0272
3	100	200	0.807 ± 0.0562	0.9357 ± 0.0187	0.3766 ± 0.0834	0.7922 ± 0.0278
4	100	300	0.8436 ± 0.0531	0.9479 ± 0.0177	0.3982 ± 0.0831	0.7994 ± 0.0277
5	300	50	0.6326 ± 0.0426	0.8775 ± 0.0142	0.2058 ± 0.0592	0.7353 ± 0.0197
6	300	100	0.7287 ± 0.0372	0.9096 ± 0.0124	0.2735 ± 0.0475	0.7578 ± 0.0158
7	300	200	0.8053 ± 0.0328	0.9351 ± 0.0109	0.2553 ± 0.0454	0.7518 ± 0.0151
8	300	300	0.8415 ± 0.0313	0.9472 ± 0.0104	0.2431 ± 0.0425	0.7477 ± 0.0142

ISSN: 1471-2105