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Table 3 Comparison with other existing three methods in the number of breast cancer-related miRNA sponge interactions and experimentally validated miRNA sponge interactions

From: Identifying miRNA sponge modules using biclustering and regulatory scores

Methods #Interactions #Breast cancer-related interactions (percentage) Validated miRNA sponge interactions #Validated interactions
miRSM_default 577544 21669 (3.75%) SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN 5
miRSM_v1 169617 6104 (3.60%) SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN 5
miRSM_v2 1228533 46186 (3.76%) SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN 5
PC 933516 28354 (3.04%) HIAT1:PTEN, SERINC1:PTEN, KLF6:PTEN, TNKS2: PTEN, PDGFRA:RB1, LRCH1:PTEN, AFF1:PTEN 7
SPPC 177371 6434 (3.63%) LRCH1:PTEN, KLF6:PTEN 2
Hermes 43144 1018 (2.36%) JARID2:PTEN, RUNX1:PTEN, AFF1:PTEN 3
  1. “:” denotes “competing with”. Three miRSM networks including miRSM_default with a = b = 0.5 and s = -0.3, miRSM_v1 with a = 0.45, b = 0.55 and s = -0.3, and miRSM_v2 with a = 0.55, b = 0.45 and s = -0.3 are used to compare