Table 3 Comparison with other existing three methods in the number of breast cancer-related miRNA sponge interactions and experimentally validated miRNA sponge interactions
From: Identifying miRNA sponge modules using biclustering and regulatory scores
Methods | #Interactions | #Breast cancer-related interactions (percentage) | Validated miRNA sponge interactions | #Validated interactions |
|---|---|---|---|---|
miRSM_default | 577544 | 21669 (3.75%) | SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN | 5 |
miRSM_v1 | 169617 | 6104 (3.60%) | SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN | 5 |
miRSM_v2 | 1228533 | 46186 (3.76%) | SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN | 5 |
PC | 933516 | 28354 (3.04%) | HIAT1:PTEN, SERINC1:PTEN, KLF6:PTEN, TNKS2: PTEN, PDGFRA:RB1, LRCH1:PTEN, AFF1:PTEN | 7 |
SPPC | 177371 | 6434 (3.63%) | LRCH1:PTEN, KLF6:PTEN | 2 |
Hermes | 43144 | 1018 (2.36%) | JARID2:PTEN, RUNX1:PTEN, AFF1:PTEN | 3 |