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Fig. 6 | BMC Bioinformatics

Fig. 6

From: SMITE: an R/Bioconductor package that identifies network modules by integrating genomic and epigenomic information

Fig. 6

SMITE-identified module implicating cell cycle and MAPK pathways. SMITE allows visualization of the relationship between each component score and the overall node score. This functional module is enriched in human genes that regulate cell cycle by altering cell survival and apoptosis consistent with the known property of T. gondii infection of human cells to induce host cell cycle arrest at G2. The module shows MAPK4 as a highly scoring gene (intense red coloring) centered within the network

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BMC Bioinformatics

ISSN: 1471-2105

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