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Table 2 LOO XERp Results for TBM vs Healthy Controls

From: Metabolomics variable selection and classification in the presence of observations below the detection limit using an extension of ERp

Variable % Selected Classification Accuracy % Average threshold Direction
Control Group Experimental Group Overall
4-hydroxyphenylpyruvic acid 100 100 82 94 0 Up
non-annotated-1 100 100 76 92 0 Up
methylcitric acid 100 94 88 92 0.45 Up
quinolinic acid 100 87 94 90 2.38 Up
2-hydroxybutyric acid 100 77 94 83 0.31 Up
2-hydroxyvaleric acid 100 77 94 83 0 Up
phenylacetylglutamine 100 90 71 83 1.02 Up
3-hydroxyisovaleric acid 100 71 100 81 20.02 Up
1,4-dihydroxycyclohexane 100 71 88 77 0.23 Up
2-ketoglutaric acid 100 65 82 71 0.53 Up
uracil 100 61 88 71 0.69 Up
non-annotated-3 75 100 71 90 0 Up
hexanoic acid 67 65 94 75 0.35 Down
isocitric acid 33 52 94 67 1.67 Up
pyruvic acid 17 81 76 79 0.25 Up
  1. The table displays an excerpt of the LOO XERp results. The table is sorted in descending order of the second column (“% Selected”), i.e. the percentage of times a variable (as listed in the first column under “Variable”) was selected out of the \( N={N}_0+{N}_1 \) LOO iterations. In addition, the table reports the specificity (accurate classification of control subjects) and sensitivity (accurate classification of experimental subjects) percentages in columns 3 and 4, as well as the overall classification accuracy in column 5. Columns 6 and 7 contain the threshold values averaged over all instances the variable was selected (“Average Threshold”) and the direction of the shift found to be significant (“Direction”)