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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Combining phylogenetic footprinting with motif models incorporating intra-motif dependencies

Fig. 3

Classification performance for PFMs with base dependencies of orders 0,1 and 2. a We show the mean and standard error of the ROC AUC for PFMs of orders 0, 1, and 2 averaged over 25–fold stratified repeated random subsampling. b We plot the mean and standard error of the relative increase of the ROC AUC for the PFMs of orders 1 and 2 relative to the PFM or order 0 for each of the 35 TFs. Taking into account base dependencies of order 1 increases the classification performance for 31 TFs. Taking into account base dependencies of order 2 increases the classification performance in all cases and is larger compared to taking into account base dependencies of order 1 in all cases. See Additional file 6 for detailed ROC and PR curves for the PFMs of order 2

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