Fig. 5
From: Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data
Log 2 peak areas for QC samples in HAPO Metabolomics across all 50 batches. Data are presented for peaks annotated as alanine, tryptamine, glucose and other aldohexoses and 1,5-anhydroglucitol. The first column contains original non-normalized observations and the second column contains mixnorm-normalized values. Small, medium and large blue dots correspond to maternal QC samples placed at the beginning (M1), middle (M2) and end (M3) of each batch, respectively. Small, medium and large pink dots correspond to newborn QC samples placed at the beginning (B1), middle (B2) and end (B3) of each batch, respectively. Dots below the dotted line represent values below the detection threshold for a given batch