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Table 2 The top 10 significant genes based on conventional differential gene expression analysis (i.e., concordance index) and dwgLASSO with prior biological knowledge incorporated, along with their adjusted p-value

From: Incorporating prior biological knowledge for network-based differential gene expression analysis using differentially weighted graphical LASSO

Top 10 significant genes based on concordance index

Top 10 significant genes based on dwgLASSO

Gene symbol

Adjusted p-value

Gene symbol

Adjusted p-value

BTD

0.000167029

SALL2

0.018149333

FKTN

0.000424976

UBE2S

0.015577505

LRRC17

0.000424976

R A B 1 1 F I P 5

0.001638818

R A B 1 1 F I P 5

0.001638818

KIAA1467

0.005012636

E M X 2

0.002384716

XBP1

0.005019825

HNRNPAB

0.002384716

KIAA0922

0.021163875

TKT

0.002805234

E M X 2

0.002384716

LANCL1

0.003481701

OAZ2

0.040090787

TFF3

0.003481701

NDC80

0.030630047

USF2

0.004094746

CCT5

0.048116117

  1. Common genes are marked in bold