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Table 2 The top 10 significant genes based on conventional differential gene expression analysis (i.e., concordance index) and dwgLASSO with prior biological knowledge incorporated, along with their adjusted p-value

From: Incorporating prior biological knowledge for network-based differential gene expression analysis using differentially weighted graphical LASSO

Top 10 significant genes based on concordance index Top 10 significant genes based on dwgLASSO
Gene symbol Adjusted p-value Gene symbol Adjusted p-value
BTD 0.000167029 SALL2 0.018149333
FKTN 0.000424976 UBE2S 0.015577505
LRRC17 0.000424976 R A B 1 1 F I P 5 0.001638818
R A B 1 1 F I P 5 0.001638818 KIAA1467 0.005012636
E M X 2 0.002384716 XBP1 0.005019825
HNRNPAB 0.002384716 KIAA0922 0.021163875
TKT 0.002805234 E M X 2 0.002384716
LANCL1 0.003481701 OAZ2 0.040090787
TFF3 0.003481701 NDC80 0.030630047
USF2 0.004094746 CCT5 0.048116117
  1. Common genes are marked in bold