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Fig. 3 | BMC Bioinformatics

Fig. 3

From: SEPIa, a knowledge-driven algorithm for predicting conformational B-cell epitopes from the amino acid sequence

Fig. 3

Predicted and observed epitope residues in the human β2AR receptor. The predicted epitope residues are in green, the observed epitopes are in red, and the residues that are both predicted and observed as epitopes are in blue. Above: amino acid sequence, with the modeled loop regions in italic and underlined. Below: structure of β2AR co-crystallized with a Fab fragment, shown as ribbons with predicted and observed epitopes in sticks; β2AR is colored in light purple with modeled regions in light pink, Fab heavy chain in dark gray and Fab light chain in light gray

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BMC Bioinformatics

ISSN: 1471-2105

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