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Table 1 Prediction performance of the individual features F1-13 and of their combination (F), for all window sizes W = 0-9, estimated by the AUC score and evaluated by 10-fold cross validation of the S85 set. The features indicate intrinsically disordered regions (F8 and F7), flexibility (F5 and F6), evolutionary information (F13), energy-like (F9), secondary structure (F4), solvent accessibility (F10 and F11), solubility (F12), hydrophilicity (F3), and amino acid composition (F1 and F2)

From: SEPIa, a knowledge-driven algorithm for predicting conformational B-cell epitopes from the amino acid sequence

  AUC score for different window sizes W
W F1 F2 F3 F4 F5 F6 F7 F8 F9 F10 F11 F12 F13 F
0 0.586 0.574 0.545 0.561 0.517 0.560 0.523 0.519 0.551 0.516 0.521 0.547 0.532 0.644
3 0.591 0.615 0.576 0.533 0.544 0.579 0.543 0.514 0.569 0.548 0.542 0.585 0.547 0.639
5 0.604 0.597 0.579 0.552 0.542 0.580 0.544 0.511 0.580 0.583 0.575 0.588 0.554 0.635
7 0.600 0.603 0.570 0.558 0.541 0.580 0.545 0.495 0.580 0.590 0.609 0.591 0.548 0.640
9 0.614 0.619 0.593 0.560 0.533 0.579 0.557 0.525 0.553 0.569 0.586 0.570 0.550 0.646
  1. Values in bold correspond to the optimal window sizes for each feature