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Table 1 Prediction performance of the individual features F1-13 and of their combination (F), for all window sizes W = 0-9, estimated by the AUC score and evaluated by 10-fold cross validation of the S85 set. The features indicate intrinsically disordered regions (F8 and F7), flexibility (F5 and F6), evolutionary information (F13), energy-like (F9), secondary structure (F4), solvent accessibility (F10 and F11), solubility (F12), hydrophilicity (F3), and amino acid composition (F1 and F2)

From: SEPIa, a knowledge-driven algorithm for predicting conformational B-cell epitopes from the amino acid sequence

 

AUC score for different window sizes W

W

F1

F2

F3

F4

F5

F6

F7

F8

F9

F10

F11

F12

F13

F

0

0.586

0.574

0.545

0.561

0.517

0.560

0.523

0.519

0.551

0.516

0.521

0.547

0.532

0.644

3

0.591

0.615

0.576

0.533

0.544

0.579

0.543

0.514

0.569

0.548

0.542

0.585

0.547

0.639

5

0.604

0.597

0.579

0.552

0.542

0.580

0.544

0.511

0.580

0.583

0.575

0.588

0.554

0.635

7

0.600

0.603

0.570

0.558

0.541

0.580

0.545

0.495

0.580

0.590

0.609

0.591

0.548

0.640

9

0.614

0.619

0.593

0.560

0.533

0.579

0.557

0.525

0.553

0.569

0.586

0.570

0.550

0.646

  1. Values in bold correspond to the optimal window sizes for each feature