From: Network-based analysis of transcriptional profiles from chemical perturbations experiments
Group ID - Main Function | Compounds | Functions |
---|---|---|
G1 - Solvents | carbon tetrach | cleaning agent |
 | chloroform | solvent |
 | dimethylformamide | solvent |
 | allyl alcohol | alcohol |
 | 1-naphthyl isothiocyanate | preservative |
 | lipo-polysaccharide | endotoxin |
G2 - Antifungals | clotrimazole | antifungal |
 | fluconazole | antifungal |
 | miconazole | antifungal |
 | mifepristone | steroid |
G3 - Statins | cerivastatin | statin |
 | fluvastatin | statin |
 | lovastatin | statin |
 | simvastatin | statin |
G4 - Estrogens | diethylstilbestrol | estrogen |
 | beta-estradiol | estrogen |
 | ethinylestradiol | estrogen |
G5 - Fibrates | aspirin | anti-inflammatory |
 | fenofibrate | fibrate |
 | gemfibrozil | fibrate |
 | bezafibrate | fibrate |
G6 - Steroids | bithionol | photosensitizer |
 | norethisterone | progestogens |
 | progesterone | progestogens |
 | retinoic acid | progestogens regulator |
G7 - n.c | atorvastatin | statin |
 | econazole | antifungal |
 | raloxifene | estrogen |
 | phenothiazine | antipsychotic |
G8 - Anti-Cancer | catechol | benzenediols |
 | azathioprine | cancer drug |
 | ifosfamide | cancer drug |
 | leflunomide | antirheumatic |
 | letrozole | cancer drug |
 | phenobarbital | anticonvulsant |
 | zomepirac | antipyretic |
 | diethylnitrosamine | tumorigenic |
G9 - Chemotherapeutics | doxorubicin | chemotherapeutic |
 | procarbazine | chemotherapeutic |
 | promethazine | neuroleptic |
 | mitomycin C | chemotherapeutic |
 | gefitinib | cancer drug |
 | erlotinib | cancer drug |
 | tandutinib | antineoplastic |
 | balsalazide | anti-inflammatory |
G10 - Alkylating, Cancer | altretamine. | alkylating |
 | lomustine | cancer drug |
 | imatinib | cancer drug |
G11 - n.c. | chlorambucil | cancer drug |
 | enoxacin | antibacterial |
 | fluphenazine | antipsychotic |
G12 - Anti-Inflamm/ Fungal | dexamethasone | anti-inflammatory |
 | itraconazole | anti-fungal |
 | ketoconazole | anti-fungal |
 | meloxicam | anti-inflammatory |
 | sulindac | anti-inflammatory |
 | 6-thioguanine | anti-inflammatory/cancer |
G13 - Antiseptics, Estrogens | clonazepam | anxiolytic |
 | cyproterone acetate | estrogenic |
 | estradiol benzoate | estrogenic |
 | safrole | antiseptic |
 | methyl salicylate | antiseptic |