Skip to main content

Table 1 Compound groups. Main functions retrieved through the STITCH database

From: Network-based analysis of transcriptional profiles from chemical perturbations experiments

Group ID - Main Function

Compounds

Functions

G1 - Solvents

carbon tetrach

cleaning agent

 

chloroform

solvent

 

dimethylformamide

solvent

 

allyl alcohol

alcohol

 

1-naphthyl isothiocyanate

preservative

 

lipo-polysaccharide

endotoxin

G2 - Antifungals

clotrimazole

antifungal

 

fluconazole

antifungal

 

miconazole

antifungal

 

mifepristone

steroid

G3 - Statins

cerivastatin

statin

 

fluvastatin

statin

 

lovastatin

statin

 

simvastatin

statin

G4 - Estrogens

diethylstilbestrol

estrogen

 

beta-estradiol

estrogen

 

ethinylestradiol

estrogen

G5 - Fibrates

aspirin

anti-inflammatory

 

fenofibrate

fibrate

 

gemfibrozil

fibrate

 

bezafibrate

fibrate

G6 - Steroids

bithionol

photosensitizer

 

norethisterone

progestogens

 

progesterone

progestogens

 

retinoic acid

progestogens regulator

G7 - n.c

atorvastatin

statin

 

econazole

antifungal

 

raloxifene

estrogen

 

phenothiazine

antipsychotic

G8 - Anti-Cancer

catechol

benzenediols

 

azathioprine

cancer drug

 

ifosfamide

cancer drug

 

leflunomide

antirheumatic

 

letrozole

cancer drug

 

phenobarbital

anticonvulsant

 

zomepirac

antipyretic

 

diethylnitrosamine

tumorigenic

G9 - Chemotherapeutics

doxorubicin

chemotherapeutic

 

procarbazine

chemotherapeutic

 

promethazine

neuroleptic

 

mitomycin C

chemotherapeutic

 

gefitinib

cancer drug

 

erlotinib

cancer drug

 

tandutinib

antineoplastic

 

balsalazide

anti-inflammatory

G10 - Alkylating, Cancer

altretamine.

alkylating

 

lomustine

cancer drug

 

imatinib

cancer drug

G11 - n.c.

chlorambucil

cancer drug

 

enoxacin

antibacterial

 

fluphenazine

antipsychotic

G12 - Anti-Inflamm/ Fungal

dexamethasone

anti-inflammatory

 

itraconazole

anti-fungal

 

ketoconazole

anti-fungal

 

meloxicam

anti-inflammatory

 

sulindac

anti-inflammatory

 

6-thioguanine

anti-inflammatory/cancer

G13 - Antiseptics, Estrogens

clonazepam

anxiolytic

 

cyproterone acetate

estrogenic

 

estradiol benzoate

estrogenic

 

safrole

antiseptic

 

methyl salicylate

antiseptic