Table 2 Groups’ internal similarity by multiple criteria
From: Network-based analysis of transcriptional profiles from chemical perturbations experiments
Group | Function | Significance of interacting proteins | Significance of common side effects |
|---|---|---|---|
G1 | Solvents | 6.61E-33 * | NA |
G2 | Antifungals | 4.45E-19 * | 8.47E-11 |
G3 | Statins | 1.69E-33 * | 1.29E-145 * |
G4 | Estrogens | NA | NA |
G5 | Fibrates | 1.02E-56 * | 6.60E-20 |
G6 | Steroids | 1.56E-06 * | NA |
G7 | n.c. (estrogens, antifungals) | 0.0002 | 1.77E-05 |
G8 | Anti-Cancer | 1.69E-06 * | 7.91E-16 |
G9 | Chemoterapeutics | 9.79E-05 | 1.78E-32 * |
G10 | Alkylating, Cancer | 0.0001 | 2.79E-07 |
G11 | n.c (anti-cancer, estrogens) | 0.0012 | 4.80E-15 |
G12 | Anti-Inflamm/ Fungal | 1.28E-18 * | 2.91E-18 |
G13 | Antiseptics, Estrogens | 0.0004 | NA |