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Fig. 1 | BMC Bioinformatics

Fig. 1

From: VacSol: a high throughput in silico pipeline to predict potential therapeutic targets in prokaryotic pathogens using subtractive reverse vaccinology

Fig. 1

Schematic diagram of the protein prioritization process. Steps to prioritize proteins to identify PVCs include: (1) the complete bacterial proteome (sequences) subjected to the VacSol pipeline for identifying PVCs; (2) the complete proteome is searched for non-host homologous, essential, virulent proteins residing in the extracellular membrane with less than two transmembrane helices; (3) proteins that meet the selection criteria are considered to be PVC proteins; (4) prioritized proteins are further analyzed for antigenic B- and T-cell epitopes

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BMC Bioinformatics

ISSN: 1471-2105

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