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Table 2 Prioritized candidate MTB-human PPIs suggested by the template domain-domain interactions that were derived from the interologs of the structurally resolved complexes in iPfam/3DID

From: Using structural knowledge in the protein data bank to inform the search for potential host-microbe protein interactions in sequence space: application to Mycobacterium tuberculosis

Joint similarity score threshold

Number of candidate pairs (number unique to interolog-based search)

Number of MTB proteins

Number of human proteins

0.75

168 (30)

64

120

0.8

87 (23)

29

73

0.9

4 (0)

2

3