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Fig. 4 | BMC Bioinformatics

Fig. 4

From: ProteoModlR for functional proteomic analysis

Fig. 4

ProteoModlR enables large-scale analysis of experimentally measured protein abundance and PTM stoichiometry. Relative abundance of four representative proteins from 2784 proteins analyzed from SILAC-labeled CD8+ T cells stimulated with IL-2, as compared to unstimulated control, and analyzed using MaxQuant [19]. T-cell receptor signaling-dependent LCK and ZAP70 proteins exhibit no changes upon IL-2 stimulation, whereas IL-2 receptor dependent STAT5A and NFIL3 exhibits increases in abundance or phosphorylation stoichiometry upon IL-2 stimulation

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