Table 1 The averages of the number of estimated edges, the five performance measures and the computation time (sec.) over 50 datasets
From: Enhanced construction of gene regulatory networks using hub gene information
p | n | Method | \(|\hat {E}|\) | SEN | SPE | FDR | MISR | MCC | Time |
|---|---|---|---|---|---|---|---|---|---|
44 | 22 | GeneNet | 0.80 | 1.00 | 99.97 | 4.38 | 5.47 | 3.25 | 0.02 |
(|E|=52) | Â | Â | (0.31) | (0.37) | (0.02) | (2.05) | (0.01) | (1.06) | (0.00) |
| Â | Â | NS | 0.66 | 1.19 | 100.00 | 2.50 | 5.44 | 6.65 | 0.03 |
| Â | Â | Â | (0.13) | (0.23) | (0.00) | (2.05) | (0.01) | (1.16) | (0.00) |
| Â | Â | SPACE | 10.48 | 12.50 | 99.55 | 33.38 | 5.23 | 24.58 | 0.01 |
| Â | Â | Â | (1.21) | (1.32) | (0.07) | (3.40) | (0.05) | (1.69) | (0.00) |
| Â | Â | ESPACE | 12.06 | 16.50 | 99.61 | 23.62 | 4.96 | 31.46 | 0.00 |
| Â | Â | Â | (1.12) | (1.33) | (0.06) | (2.52) | (0.05) | (1.67) | (0.00) |
| Â | Â | GLASSO | 6.64 | 6.88 | 99.66 | 33.86 | 5.44 | 17.98 | 0.00 |
| Â | Â | Â | (0.95) | (0.66) | (0.08) | (4.12) | (0.06) | (1.19) | (0.00) |
| Â | Â | GLASSO-SF | 7.14 | 6.77 | 99.60 | 32.51 | 5.51 | 17.39 | 0.04 |
| Â | Â | Â | (1.20) | (0.70) | (0.10) | (4.11) | (0.07) | (1.12) | (0.00) |
| Â | Â | EGLASSO | 6.34 | 8.65 | 99.79 | 26.36 | 5.22 | 22.14 | 0.00 |
| Â | Â | Â | (0.74) | (0.96) | (0.04) | (3.47) | (0.04) | (1.49) | (0.00) |
| Â | Â | PCACMI | 55.60 | 33.15 | 95.71 | 68.93 | 7.73 | 27.98 | 0.21 |
| Â | Â | Â | (0.62) | (0.73) | (0.07) | (0.65) | (0.08) | (0.71) | (0.01) |
| Â | Â | CMI2NI | 59.34 | 35.38 | 95.42 | 68.92 | 7.88 | 28.97 | 0.50 |
| Â | Â | Â | (0.73) | (0.70) | (0.07) | (0.57) | (0.08) | (0.63) | (0.07) |
| Â | 44 | GeneNet | 9.28 | 13.58 | 99.75 | 12.19 | 4.99 | 29.73 | 0.02 |
| Â | Â | Â | (1.32) | (1.48) | (0.07) | (2.11) | (0.05) | (1.61) | (0.00) |
| Â | Â | NS | 4.16 | 7.65 | 99.98 | 3.48 | 5.10 | 25.92 | 0.03 |
| Â | Â | Â | (0.23) | (0.42) | (0.01) | (1.26) | (0.02) | (0.75) | (0.00) |
| Â | Â | SPACE | 27.28 | 37.38 | 99.12 | 25.79 | 4.27 | 48.78 | 0.01 |
| Â | Â | Â | (1.50) | (1.73) | (0.08) | (1.47) | (0.07) | (1.71) | (0.00) |
| Â | Â | ESPACE | 23.12 | 34.38 | 99.41 | 20.03 | 4.16 | 50.01 | 0.00 |
| Â | Â | Â | (1.20) | (1.36) | (0.07) | (1.47) | (0.06) | (0.94) | (0.00) |
| Â | Â | GLASSO | 11.32 | 13.12 | 99.50 | 26.48 | 5.25 | 27.20 | 0.00 |
| Â | Â | Â | (1.35) | (1.08) | (0.10) | (3.03) | (0.05) | (0.99) | (0.00) |
| Â | Â | GLASSO-SF | 13.62 | 14.38 | 99.31 | 30.92 | 5.36 | 26.77 | 0.04 |
| Â | Â | Â | (1.52) | (1.23) | (0.11) | (3.22) | (0.07) | (1.16) | (0.00) |
| Â | Â | EGLASSO | 14.34 | 22.38 | 99.70 | 16.31 | 4.55 | 39.94 | 0.00 |
| Â | Â | Â | (1.10) | (1.63) | (0.04) | (1.81) | (0.07) | (1.73) | (0.00) |
| Â | Â | PCACMI | 26.70 | 34.00 | 98.99 | 33.39 | 4.58 | 45.47 | 0.18 |
| Â | Â | Â | (0.44) | (0.70) | (0.05) | (1.28) | (0.07) | (0.89) | (0.00) |
| Â | Â | CMI2NI | 28.84 | 35.50 | 98.84 | 35.75 | 4.64 | 45.54 | 0.27 |
| Â | Â | Â | (0.48) | (0.67) | (0.04) | (0.96) | (0.06) | (0.74) | (0.01) |