Table 4 The averages of the number of estimated edges, the five performance measures and the computation time (sec.) over 50 datasets
From: Enhanced construction of gene regulatory networks using hub gene information
p | n | Method | \(|\hat {E}|\) | SEN | SPE | FDR | MISR | MCC | Time |
|---|---|---|---|---|---|---|---|---|---|
612 | 306 | GeneNet | 597.72 | 55.42 | 99.93 | 22.24 | 0.27 | 65.49 | 3.91 |
(|E|=837) | Â | Â | (4.89) | (0.22) | (0.00) | (0.41) | (0.00) | (0.15) | (0.03) |
| Â | Â | NS | 343.52 | 41.00 | 100.00 | 0.10 | 0.26 | 63.91 | 5.72 |
| Â | Â | Â | (0.86) | (0.10) | (0.00) | (0.03) | (0.00) | (0.08) | (0.07) |
| Â | Â | SPACE | 781.04 | 66.72 | 99.88 | 28.21 | 0.27 | 69.02 | 16.57 |
| Â | Â | Â | (8.90) | (0.31) | (0.00) | (0.55) | (0.00) | (0.22) | (0.14) |
| Â | Â | ESPACE | 765.50 | 67.36 | 99.89 | 26.22 | 0.25 | 70.35 | 3.69 |
| Â | Â | Â | (5.95) | (0.29) | (0.00) | (0.41) | (0.00) | (0.22) | (0.05) |
| Â | Â | GLASSO | 1097.32 | 65.66 | 99.71 | 49.86 | 0.45 | 57.15 | 4.86 |
| Â | Â | Â | (6.08) | (0.18) | (0.00) | (0.25) | (0.00) | (0.17) | (0.37) |
| Â | Â | GLASSO-SF | 1069.56 | 60.67 | 99.70 | 52.38 | 0.48 | 53.45 | 29.36 |
| Â | Â | Â | (14.93) | (0.64) | (0.01) | (0.29) | (0.00) | (0.27) | (1.85) |
| Â | Â | EGLASSO | 1042.64 | 67.86 | 99.74 | 45.43 | 0.40 | 60.63 | 7.59 |
| Â | Â | Â | (8.54) | (0.34) | (0.00) | (0.28) | (0.00) | (0.18) | (0.65) |
| Â | Â | PCACMI | 272.08 | 27.40 | 99.98 | 15.70 | 0.35 | 47.94 | 42.09 |
| Â | Â | Â | (0.99) | (0.11) | (0.00) | (0.24) | (0.00) | (0.14) | (1.41) |
| Â | Â | CMI2NI | 297.72 | 29.12 | 99.97 | 18.12 | 0.35 | 48.70 | 68.89 |
| Â | Â | Â | (1.19) | (0.11) | (0.00) | (0.22) | (0.00) | (0.13) | (1.71) |
| Â | 612 | GeneNet | 727.94 | 68.80 | 99.92 | 20.80 | 0.22 | 73.69 | 5.56 |
| Â | Â | Â | (4.53) | (0.20) | (0.00) | (0.32) | (0.00) | (0.13) | (0.06) |
| Â | Â | NS | 453.50 | 54.14 | 100.00 | 0.08 | 0.21 | 73.47 | 25.69 |
| Â | Â | Â | (1.19) | (0.14) | (0.00) | (0.02) | (0.00) | (0.10) | (0.38) |
| Â | Â | SPACE | 983.38 | 84.01 | 99.85 | 28.39 | 0.22 | 77.43 | 62.72 |
| Â | Â | Â | (6.38) | (0.24) | (0.00) | (0.34) | (0.00) | (0.17) | (1.41) |
| Â | Â | ESPACE | 983.84 | 84.96 | 99.85 | 27.66 | 0.21 | 78.28 | 17.86 |
| Â | Â | Â | (4.88) | (0.19) | (0.00) | (0.27) | (0.00) | (0.14) | (0.63) |
| Â | Â | GLASSO | 1467.52 | 85.61 | 99.60 | 51.15 | 0.47 | 64.47 | 29.86 |
| Â | Â | Â | (5.04) | (0.11) | (0.00) | (0.17) | (0.00) | (0.12) | (1.21) |
| Â | Â | GLASSO-SF | 1615.16 | 85.60 | 99.52 | 55.61 | 0.55 | 61.42 | 117.78 |
| Â | Â | Â | (6.56) | (0.13) | (0.00) | (0.17) | (0.00) | (0.13) | (3.68) |
| Â | Â | EGLASSO | 1385.60 | 87.87 | 99.65 | 46.89 | 0.40 | 68.14 | 38.67 |
| Â | Â | Â | (5.37) | (0.12) | (0.00) | (0.20) | (0.00) | (0.14) | (1.35) |
| Â | Â | PCACMI | 273.22 | 27.68 | 99.98 | 15.20 | 0.35 | 48.33 | 39.25 |
| Â | Â | Â | (0.98) | (0.11) | (0.00) | (0.17) | (0.00) | (0.12) | (0.59) |
| Â | Â | CMI2NI | 298.38 | 29.55 | 99.97 | 17.10 | 0.34 | 49.37 | 59.62 |
| Â | Â | Â | (0.97) | (0.09) | (0.00) | (0.11) | (0.00) | (0.09) | (0.84) |