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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Bacterial protein meta-interactomes predict cross-species interactions and protein function

Fig. 3

Conserved and cross-functional interactions in the consensus meta-interactome. a Counts of PPIs in the consensus meta-interactome network. Nspecies indicates the number of distinct bacterial species contributing the interaction; a value of 1 denotes an interaction observed for a single species only. For each count, subsets denote how many PPIs involve two, one, or zero interactors of known function (as both, one, and none, respectively). b Significant connections between functional classes are mediated by the underlying PPIs in the consensus meta-interactome. For each class combination we calculated a Z-score that reflects the significance of the interaction density between classes and class coverage. While interactions mostly appear between the same classes, we also observe that most functional cross-talk emanates from OGs with translational as well as posttranslational functions

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