Bacterial protein meta-interactomes predict cross-species interactions and protein function

BMC Bioinformatics

Table 1 Comprehensive experimental microbial interactome sizes

Species Name	Interactome size (PPIs)	Unique OGs in proteome	Proteins in proteome	Proteins in interactome	Ref.
C. jejuni	11,687	1523	1623	1321	[29]
E. coli	2234	2563	4306	1269	[8]
H. pylori	3004	1280	1553	739	[12]
M. loti	3121	2981	7272	1804	[23]
Synechocystis sp.	3236	2246	3575	1920	[47]
T. pallidum	3649	736	1036	726	[17]
S. cerevisiae	4,549^a	4794	6721	3278	[50]
S. cerevisiae	957^a	4794	6721	1004	[51]
S. cerevisiae	1,809^a	4794	6721	2018	[52]
S. cerevisiae	2,770^a	4794	6721	1124	[53]

^aSambourg et al. [44] estimated the yeast interactome size to be ~37,000 PPIs, based on 3042 interactions among well-studied proteins curated from the literature

ISSN: 1471-2105