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Fig. 2 | BMC Bioinformatics

Fig. 2

From: QuickMIRSeq: a pipeline for quick and accurate quantification of both known miRNAs and isomiRs by jointly processing multiple samples from microRNA sequencing

Fig. 2

Database preparation. a The flowchart of creation of modified miRNA and hairpin database. b Mature miRNAs with identical sequences. c Sequences from a model miRNA cluster; i.e., different miRNAs mapping (and overlapping) to a region of the same hairpin precursor. d The same pre-miRNA gene loci can generate many miRNA isoforms, but the most abundant isoform in a particular sample may not necessarily be the one annotated in miRBase. The numbers in the first column represent counts of sequences identical to the sequences in the second column. e A mature miRNA can be derived from more than one precursor. f Representative entries in a *miRNA database. All extended bases are in lower case, while the nucleotides that correspond to mature miRNAs are in upper case

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