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Fig. 3 | BMC Bioinformatics

Fig. 3

From: QuickMIRSeq: a pipeline for quick and accurate quantification of both known miRNAs and isomiRs by jointly processing multiple samples from microRNA sequencing

Fig. 3

Various strategies introduced in QuickMIRSeq to reduce computational time and to improve accuracy in miRNA quantification. a The overview of workflow for miRNA-seq data analysis. b Collapsing identical reads into unique ones within and across multiple samples. c Remapping of miRNA reads with mismatches to the reference genome to reduce false hits. d miRNAs has-miR-3913-5p and has-miR-3913-3p are generated from the same hairpin precursor and reverse complementary to each other. e Genes hsa-mir-374b and hsa-mir-374c are expressed from the same genomic locus in chromosome X but transcribed in opposite directions

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BMC Bioinformatics

ISSN: 1471-2105

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