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Table 1 Results of the topological analysis

From: The autophagy interaction network of the aging model Podospora anserina

Topology Pred. net. Rand. net. Test statistic p-value
Diameter 8 6 Relative frequencies 0.007
Modularity 0.57 0.32 Shapiro-Wilk + Norm.dist 1.22e−13
Transitivity 0.35 0.12 Shapiro-Wilk + Norm.dist. 2.74e−42
Betweenness NA NA Kolmogorov-Smirnov 1.17e−08
Degrees NA NA Kolmogorov-Smirnov 0.09
  1. Different test procedures were applied according to the corresponding topological feature (see “Methods” section and Additional file 5). The topological values of the predicted network and the median values of the random networks are listed. In addition, the corresponding p-values are shown, indicating the significance of the difference between the random and the predicted network. The computation of a single topological value for transitivity and betweenness was not applicable, since each node of each network has one betweenness and one degree. Here, only the distributions had been compared using the Kolmogorov-Smirnoff test