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Fig. 6 | BMC Bioinformatics

Fig. 6

From: AD-LIBS: inferring ancestry across hybrid genomes using low-coverage sequence data

Fig. 6

Illustration of cases where either a local ancestry detection method (like AD-LIBS) or a global ancestry detection (like \( \widehat{f} \)) might succeed, partially succeed, or fail. Each line represents a chromosome, with polar bear ancestry shown in blue and brown bear ancestry shown in brown. All five individuals needed for computation of \( \widehat{f} \) are shown in each case. a local and global methods both succeed in detecting all of the hybrid individual’s polar bear ancestry. b local and global methods both fail to detect the hybrid individual’s polar bear ancestry. c local methods successfully detect the hybrid individual’s polar bear ancestry, since it is in a different part of the genome than the polar bear ancestry in the genome of the model “unadmixed” brown bear. Global methods fail to detect the hybrid individual’s polar bear ancestry. Since global methods use genome-wide averages, the hybrid individual is not seen to possess any more polar bear ancestry than the model “unadmixed” brown bear. d Both local and global methods will detect the hybrid’s first segment of polar bear ancestry but fail to detect the second segment, resulting in both types of methods underestimating the hybrid individual’s true percent polar bear ancestry

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