AD-LIBS: inferring ancestry across hybrid genomes using low-coverage sequence data

BMC Bioinformatics

Table 1 The accuracy of AD-LIBS ancestry inferences using simulated genomes

Model	Ancestry state	Prop. calls correct	Prop. truth detected
Migration	AA	0.8858	0.9310
Migration	AB	0.8447	0.9633
Migration	BB	0.9762	0.8459
Migration	Average	0.9022	0.9134
Migration	Overall accuracy	0.9069
Single-pulse	AA	0.8933	0.9245
Single-pulse	AB	0.8170	0.9513
Single-pulse	BB	0.9501	0.7134
Single-pulse	Average	0.8868	0.8631
Single-pulse	Overall accuracy	0.8694

Two demographic models representative of the ABC Islands bears’ history were used: one in which a single admixture event between polar and brown bears takes place 12,000 years ago, followed by isolation of the hybrid population (Single-pulse model), and one in which admixture takes place at the same time but is followed by continuous brown bear migration from the mainland (Migration model). Overall accuracy is the percent of all bases for which true ancestry matched AD-LIBS-inferred ancestry. Since this number is weighted toward more common ancestry states, the average across all three ancestry states is also given

ISSN: 1471-2105