DisBind: A database of classified functional binding sites in disordered and structured regions of intrinsically disordered proteins

Table 1 The number of residues and binding residues of IDPs and IDRs according to binding partners of IDPs in DisBind

Category	# IDPs^a	# all Residues			# Residues in IDRs		# Binding Residues
Category	# IDPs^a	IDPs^b	IDRs	ORs	Helix^c	Sheet^c	IDPs	IDRs	ORs
ALL	226	166235	29908	136327	1705	439	4232	1396	2836
Protein	127	57586	12822	44764	1299	244	2984	1070	1914
RNA	12	6040	1286	4754	106	131	258	189	69
DNA	32	12092	2853	9239	301	64	383	55	328
Metal	81	40351	6242	34109	-	-	350	69	281
Cofactor	12	6825	1193	5632	-	-	41	2	39
Substrate	32	5791	1014	4777	-	-	61	2	59
ATP/GTP	32	14695	2475	12220	-	-	37	1	36
Others	44	22855	2023	20832	-	-	123	8	115

^aSome IDPs can bind to different partners. ^b# of residues or binding residues in IDPs refer to all residues or all binding residues regardless if they are in structured, unstructured, or unannotated regions. ^c# of helical or sheet residues in IDRs
Please note that IDPs may contain both structured regions and IDRs as well as un-annotated regions

ISSN: 1471-2105