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Table 2 Empirical type 1 error estimates (M = 3)

From: On the association analysis of CNV data: a fast and robust family-based association method

 

Significance Level

.005

.05

.1

.2

BSC

T1

0.0060 ± 0.0021

0.0504 ± 0.0061

0.1018 ± 0.0084

0.2082 ± 0.0113

T2

0.0056 ± 0.0021

0.0550 ± 0.0063

0.1008 ± 0.0086

0.2072 ± 0.0112

MSC

T1

0.0048 ± 0.0019

0.0486 ± 0.0060

0.1006 ± 0.0083

0.2104 ± 0.0113

T2

0.0048 ± 0.0019

0.0472 ± 0.0059

0.0956 ± 0.0082

0.1884 ± 0.0108

WSC

T1

0.0056 ± 0.0021

0.0516 ± 0.0061

0.0962 ± 0.0082

0.2006 ± 0.0111

T2

0.0048 ± 0.0019

0.0498 ± 0.0060

0.0968 ± 0.0082

0.1922 ± 0.0109

  1. The 95% confidence intervals of empirical type I error estimates for the proposed methods were calculated from 5000 replicates at four significance levels under BSC, MSC and WSC, when there are three copy number clusters