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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Genetic sequence-based prediction of long-range chromatin interactions suggests a potential role of short tandem repeat sequences in genome organization

Fig. 1

Pipeline for predicting locus-specific long-range chromatin interactions using the genetic sequence. In the contact matrix, cells denoted by filled orange boxes correspond to loci that are called significantly interacting with the LoI in all replicates of any experiment profiling chromatin interactions. This constitutes the positive set of sequences for the corresponding classifier. Those denoted by filled black boxes correspond to loci that are not called significantly interacting in any of the replicates. This constitutes the negative set of sequences for the corresponding classifier. This leaves those loci which are called significantly interacting in at least one, but not in all of the replicates. They are visualized by unfilled boxes and are not used by the classifier. The genomic loci along the columns of the contact matrix (c1, c2, c3,...,cN) are the LoI for which we build locus-specific classifiers

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