Homology to peptide pattern for annotation of carbohydrate-active enzymes and prediction of function

BMC Bioinformatics

Table 3 Annotation of 12 bacterial genomes

Method	CAZy^a	Hotpep	dbCAN web	dbCAN download
Annotated proteins	1768	1839	2300	1749
True positives	-	1546	1701	1571
False positives	-	296	599	178
False negatives	-	220	67	197
Sensitivity	-	0.88	0.87	0.89
Precision	-	0.84	0.71	0.90
F1 score	-	0.86	0.84	0.89

ISSN: 1471-2105