Fig. 1From: Segmentum: a tool for copy number analysis of cancer genomesSegmentum pipeline. Normal and tumor RDs are used to calculate RD log-ratios. RD log-ratios are then corrected for biases. BAF data are simultaneously mirrored and smoothed. Using RD log-ratios and BAF, the genome is segmented with a double sliding window method. Segmentation results are used to identify cnLOH regions in the genome (see the following sections for more details on each step)Back to article page