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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Segmentum: a tool for copy number analysis of cancer genomes

Fig. 1

Segmentum pipeline. Normal and tumor RDs are used to calculate RD log-ratios. RD log-ratios are then corrected for biases. BAF data are simultaneously mirrored and smoothed. Using RD log-ratios and BAF, the genome is segmented with a double sliding window method. Segmentation results are used to identify cnLOH regions in the genome (see the following sections for more details on each step)

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