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Table 1 DTI-GWAS Task List. Our ENIGMA-Viewer is designed for these analytical tasks

From: ENIGMA-Viewer: interactive visualization strategies for conveying effect sizes in meta-analysis

Index

Task

Example questions

1

Viewing distribution,

What is the most affected brain region under a certain disorder?

 

consistency, or

What is the overall data distribution of the effect size in all studies?

 

inconsistency

Are the results consistent or very different?

2

Detect trends

What is the distribution of cortical thicknesses and FA values?

  

How does effect size vary among studies?

3

Find association

What are the disorder (brain regions) and genetics correlates to risk?

  

How does brain structural change associated with

  

behavioral risks and changes and vulnerability?

  

How do geographical factors affect disease expression in the brain?

4

Locate extremes

What are the significant brain regions mostly affected by diseases?

5

Find local relationships

What are the differences between studies in terms of their effect size?

6

Compare different disorders

What are the common and different effects in the brain networks

  

between or among multiple disorders?

7

Compare disorders by regions

What are the regions affected or unique to a certain disorder?