Fig. 4From: Drug repositioning for enzyme modulator based on human metabolite-likenessSphingolipid metabolism pathway in Gaucher disease. Gaucher disease is caused by a deficiency in the glucocerebrosidase enzyme. Miglustat inhibits the ceramide glucosyltransferase enzyme to reduce the glucocerebroside which accumulates in Gaucher disease. Glc, glucose; Gal, galactoseBack to article page