Table 3 Predicted drug repositioning candidates for Gaucher disease
From: Drug repositioning for enzyme modulator based on human metabolite-likeness
Drug Name | Original Indication | References |
|---|---|---|
Framycetin | Aminoglycosides (Aminocyclitols) | [54] |
Amikacin | Aminoglycosides (Aminocyclitols) | |
Tobramycin | Aminoglycosides (Aminocyclitols) | |
Gentamicin | Aminoglycosides (Aminocyclitols) | |
Netilmicin | Aminoglycosides (Aminocyclitols) | |
Neomycin | Aminoglycosides (Aminocyclitols) | |
Kanamycin | Aminoglycosides (Aminocyclitols) | |
Ribostamycin | Aminoglycosides (Aminocyclitols) | |
Arbekacin | Aminoglycosides (Aminocyclitols) | |
Acarbose | Alpha-glucosidase inhibitors | [56] |
Miglitol | Alpha-glucosidase inhibitors | |
Bimatoprost | Anti-hypertension | |
Aliskiren | Anti-hypertension | |
Tacrolimus | Immunosuppressant | |
Sirolimus | Immunosuppressant | |
Everolimus | Immunosuppressant |