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Table 3 Predicted drug repositioning candidates for Gaucher disease

From: Drug repositioning for enzyme modulator based on human metabolite-likeness

Drug Name Original Indication References
Framycetin Aminoglycosides (Aminocyclitols) [54]
Amikacin Aminoglycosides (Aminocyclitols)
Tobramycin Aminoglycosides (Aminocyclitols)
Gentamicin Aminoglycosides (Aminocyclitols)
Netilmicin Aminoglycosides (Aminocyclitols)
Neomycin Aminoglycosides (Aminocyclitols)
Kanamycin Aminoglycosides (Aminocyclitols)
Ribostamycin Aminoglycosides (Aminocyclitols)
Arbekacin Aminoglycosides (Aminocyclitols)
Acarbose Alpha-glucosidase inhibitors [56]
Miglitol Alpha-glucosidase inhibitors
Bimatoprost Anti-hypertension [57,58,59]
Aliskiren Anti-hypertension
Tacrolimus Immunosuppressant
Sirolimus Immunosuppressant
Everolimus Immunosuppressant