Fig. 4
From: Contextualization of drug-mediator relations using evidence networks
a Condition-specific dependency network (CDN) for TG-101348 for drug-sensitive cell lines. Dashed lines represent statistical dependencies while solid lines represent known interactions. Size of nodes represents node essentiality. b CDN for TG-101348 for drug-insensitive cell lines. c Evidence network for the TG-101348 – DAPK3 drug-mediator pair. All edges represent a known association based from the STRING/STITCH databases. Blue edges represent mediator-gene associations. Red edges represent drug-gene associations. The yellow edge represents a direct drug-mediator association