Table 2 Comparison of HLA typing accuracies using HapMap data
From: HLAscan: genotyping of the HLA region using next-generation sequencing data
Gene | A | B | C | DQB1 | DRB1 | |||||
|---|---|---|---|---|---|---|---|---|---|---|
# alleles | 36 | 36 | 22 | 92 | 90 | |||||
Methods | HLA reporter | HLA scan | HLA reporter | HLA scan | HLA reporter | HLA scan | HLA reporter | HLA scan | HLA reporter | HLA scan |
Phase | 5 | - | 6 | - | 4 | - | 0 | - | 2 | - |
Inaccurate (2-digit) | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 3 |
Inaccurate* (4-digit) | 7 | 0 | 6 | 0 | 1 | 2 | 10 | 8 | 4 | 4 |
Accuracy (2-digit) | 100% | 100% | 100% | 100% | 100% | 100% | 98.9% | 100% | 97.8% | 96.7% |
Accuracy (4-digit) | 80.5% | 100% | 83.3% | 100% | 95.5% | 90.9% | 89.1% | 91.3% | 95.6% | 95.6% |